Detalhe da pesquisa
1.
Spliceosomal disruption of the non-canonical BAF complex in cancer.
Nature
; 574(7778): 432-436, 2019 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-31597964
2.
Coordinated alterations in RNA splicing and epigenetic regulation drive leukaemogenesis.
Nature
; 574(7777): 273-277, 2019 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-31578525
3.
BET inhibitor resistance emerges from leukaemia stem cells.
Nature
; 525(7570): 538-42, 2015 Sep 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-26367796
4.
Robust patient-derived xenografts of MDS/MPN overlap syndromes capture the unique characteristics of CMML and JMML.
Blood
; 130(4): 397-407, 2017 07 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-28576879
5.
Recurrent CDKN1B (p27) mutations in hairy cell leukemia.
Blood
; 126(8): 1005-8, 2015 Aug 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-26065650
6.
Modeling CBL activating mutations in vivo.
Blood
; 129(15): 2046-2048, 2017 04 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-28408421
7.
Menin inhibitor MI-3454 induces remission in MLL1-rearranged and NPM1-mutated models of leukemia.
J Clin Invest
; 130(2): 981-997, 2020 02 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-31855575
8.
Altered Nuclear Export Signal Recognition as a Driver of Oncogenesis.
Cancer Discov
; 9(10): 1452-1467, 2019 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-31285298
9.
Therapeutic Targeting of RNA Splicing Catalysis through Inhibition of Protein Arginine Methylation.
Cancer Cell
; 36(2): 194-209.e9, 2019 08 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-31408619
10.
Synthetic Lethal and Convergent Biological Effects of Cancer-Associated Spliceosomal Gene Mutations.
Cancer Cell
; 34(2): 225-241.e8, 2018 08 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-30107174
11.
H3B-8800, an orally available small-molecule splicing modulator, induces lethality in spliceosome-mutant cancers.
Nat Med
; 24(4): 497-504, 2018 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-29457796
12.
ASXL2 is essential for haematopoiesis and acts as a haploinsufficient tumour suppressor in leukemia.
Nat Commun
; 8: 15429, 2017 05 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-28516957
13.
Therapeutic targeting of splicing in cancer.
Nat Med
; 22(9): 976-86, 2016 09 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-27603132
14.
Modulation of splicing catalysis for therapeutic targeting of leukemia with mutations in genes encoding spliceosomal proteins.
Nat Med
; 22(6): 672-8, 2016 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-27135740
15.
Diverse and Targetable Kinase Alterations Drive Histiocytic Neoplasms.
Cancer Discov
; 6(2): 154-65, 2016 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-26566875
16.
The mutational landscape of paroxysmal nocturnal hemoglobinuria revealed: new insights into clonal dominance.
J Clin Invest
; 124(10): 4227-30, 2014 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-25244089
17.
Erratum: Modulation of splicing catalysis for therapeutic targeting of leukemia with mutations in genes encoding spliceosomal proteins.
Nat Med
; 22(6): 692, 2016 06 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-27270779